Antiparasitic Therapy Reduces Seizures in Neurocysticercosis.

Jan. 14, 2007 — Antiparasitic therapy is appropriate and reduces the symbol of seizures associated with neurocysticercosis, according to the results of a double-blind, randomized test published in the Jan. 15 matter of the New England Diary of Medical specialty. The editorialist agrees.
"Neurocysticercosis is the main drive of adult-onset seizures in the developing socio-economic class," write Héctor H. Garcia, MD, and colleagues from the Cysticercosis Working Set in Lima, Peru. "Whether therapy with antiparasitic agents results in improved attack restraint has been questioned because of the lack of adequate, controlled studies."
In this thoughtfulness, 120 patients with people cysticerci in the mentality and seizures treated with antiepileptic drugs received either 800 mg of albendazole and 6 mg of dexamethasone daily or two placebos for 10 days. Follow-up continued for 30 months or until patients were seizure-free for six months after tapering doses of their antiepileptic drugs.
In the albendazole grouping, the numeral of seizures decreased by 46% (95% self-confidence measure [CI], –74% to 83%) during months 2 to 30 after discourse. Although the alteration in sum amount of seizures and in definite quantity of harmonic seizures was not statistically significant, the act of seizures with colligation decreased significantly by 67% (95% CI, 20% to 86%).